Retrosynthesis Enhancement: Stereochemistry Improvements
Retrosynthesis in CAS SciFinder has been enhanced with more precise stereochemical labeling. Relevance ranking of evidence has been updated to reflect the more precise labeling.
In addition, coverage of unique stereoselective transformations has been extended by 30%.
Finally, new filtering options have been introduced on alternative steps to narrow by stereochemistry.
CAS Lexicon Enhancement: Include CAS Lexicon Search Terms in Search History and Detailed History Download
Improvements have been made to CAS Lexicon to better describe searches performed when viewing Search History. Additional details such as preferred concept, broader terms, narrower terms, and related terms are now presented to more accurately describe the search performed and to indicate the relationship between the searched terms.
The detailed search history download has also been enhanced to provide details on CAS Lexicon searches performed.
Reference Detail Download Enhancement: Include Reactions
Reference exports have been updated to include reactions information when present. When exporting a reference result set details or a reference detail page, a new option to include reactions data is presented.
In the resulting exported file, reaction data is present along with links to view the reaction set as well as individual reactions.
Retrosynthesis Enhancement: Improved Price Estimation
Retrosynthesis has been improved with AI-optimized plan pricing estimates for commercially available compounds with limited or incomplete price information.